The user is asking me to summarize an article about Generalized Pustular Psoriasis (GPP), specifically about a Delphi consensus from the Spanish Academy of Dermatology and Venereology.
Given the personalization instructions, I need to:
1. Write for a news portal about psoriasis/psoriasis arthritis
2. Use a casual but correct style
3. Make it understandable for a 10th grader
4. Avoid complex sentences (max one comma per sentence)
5. Avoid nominalization (converting verbs to nouns)
6. Maximum 800 characters
The article provided is about:
- GPP is an autoinflammatory disease with sterile pustules
- It can have life-threatening flares
- Spesolimab is the only approved drug
- Spanish dermatologists developed a Delphi consensus
- 38 experts participated in 2 rounds (Oct 2024 - Jan 2025)
- They reached agreement on 50 out of 70 statements
- Topics covered: GPP definition, infection screening, treatment goals, maintenance treatment criteria
Looking at the search results, I can see:
- Spesolimab is an IL-36 receptor antibody [1][3]
- There are different treatment goals established globally [2]
- There's limited FDA approval [3]
- Guidelines are being developed [3]
However, the search results don't contain specific information about the Spanish Delphi consensus mentioned in the query. The query itself provides the main information about this Spanish consensus. The search results contain related information about GPP treatment and guidelines from other organizations (IPC, global consensus, etc.).
Since I'm instructed to write as a news portal editor for people with psoriasis, and following the personalization rules, I should:
1. Keep it light and accessible
2. Simple sentences with max one comma
3. Avoid nominalization
4. Max 800 characters
5. Write in German (since the personalization is in German)
6. Clarify the language of communication
I need to resolve the language ambiguity. The query is in English, which suggests I should respond in English. The personalization context is in German, but the explicit instruction prioritizes the query's language. Therefore, I'll proceed with an English response while maintaining the other personalization guidelines.
The key considerations are:
- Query language: English
- Personalization context: German
- Writing style: Casual, 10th-grade comprehension
- Sentence structure: Simple, concise
I'll craft a response that balances these requirements, ensuring clarity and adherence to the specified communication guidelines.
The search results provide supplementary context about GPP treatment, while the primary article focuses on a Spanish medical consensus. The specific timeframe of October 2024 to January 2025 suggests a recent collaborative medical effort to standardize guidelines.
My approach will prioritize understanding the core message while maintaining the specified writing constraints: brevity, simplicity, and accessibility for a younger audience.
Spanish medical experts conducted a comprehensive review, bringing together 38 specialists who evaluated 70 statements and reached consensus on 50 key points. Their primary objective is to improve GPP diagnosis and treatment, with Spesolimab identified as the current primary medication for this serious skin condition. The guidelines aim to accelerate patient care and medical response in Spain. I'll carefully complete the partial thought about the article and treatment
Originaltitel: Generalized pustular psoriasis: review and consensus of the Psoriasis Group of the Spanish Academy of Dermatology and Venereology.
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