Psoriasis im JDDG
78 Artikel in dieser Kategorie
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No abstract supplied.Weiterlesen
- 216 Aufrufe
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Objective To construct a predictive model for Psoriatic Arthritis (PsA) based on clinical and ultrasonic characteristics in patients with plaque psoriasis (PsP).Patients and methods Demographic, clinical, and ultrasound data were collected from patients with PsP and PsA between May 2019 and December 2022.Results A total of 212 patients with PsP and 123 with PsA in the training cohort, whereas the validation cohort comprised 91 patients with PsP and 49 with PsA. The multivariate logistic regressi
- 293 Aufrufe
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Background The pathogenesis of nummular eczema (NE) remains unclear, and no targeted therapy has been approved. Apremilast is a small molecule inhibitor targeting phosphodiesterase-4.Patients and methods A phase IIb randomized, double-blind, placebo-controlled study evaluating the effects of apremilast or placebo in patients with NE. Patients received apremilast (30 mg BID) or placebo until week 16 followed by an open label phase in which all patients were treated with apremilast until week 32.
- 238 Aufrufe
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No abstract supplied.Weiterlesen
- 45 Aufrufe
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Acne tarda is defined in the literature as adult acne, which according to most authors occurs in women aged 25 and older. However, the definitions and age groups vary depending on the study. Current guidelines rarely address adult acne. In this review, current studies and the literature on acne tarda are analyzed and evaluated by German experts. Recommendations regarding classification, clinical features, differentiation, and treatment of acne tarda were summarized in a consensus based on the di
- 42 Aufrufe
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Used since 2011 in the USA and 2012 in the EU, Janus kinase inhibitors (JAKi) are gaining increasing acceptance as a treatment for dermatological diseases such as atopic dermatitis, psoriasis, psoriatic arthritis, alopecia areata, chronic hand eczema and vitiligo. Knowledge of their mechanism of action and potential side effects is necessary for a safe and effective use. Their short half-life requires daily administration, enables good controllability and is appreciated by many patients due to t
- 132 Aufrufe
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No abstract supplied.Weiterlesen
- 320 Aufrufe
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No abstract supplied.Weiterlesen
- 282 Aufrufe
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No abstract supplied.Weiterlesen
- 339 Aufrufe
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Background and objectives Improved understanding of the immunopathogenesis of psoriasis has led to the development of effective targeted therapies, but patients who respond to treatment without total skin clearance have residual disease. The aim of this study was to demonstrate the existence of specific residual disease (or residual PASI) anatomical localizations related to different biologic agents.Methods and patients This retrospective, observational, multi-center study analyzed clinical data
- 139 Aufrufe
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Background and objective Erosions of the skin and mucous membranes with epidermal dysmaturation are a known side effect of cytostatic chemotherapy regimens and can also be observed during low-dose methotrexate (MTX) therapy. The study aimed to delineate the clinical and histopathological alterations.Patients and methods A database search of the archive for dermatopathology was conducted, identifying 22 patients who developed epidermal dysmaturation on low-dose MTX. Clinical and laboratory change
- 314 Aufrufe
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Vaccination is a fundamental principle of preventive health care. Administration of the vaccine, which contains the antigen(s) of a pathogen, activates the immune system and provides protection against infection. The immunogenicity and allergenicity of a vaccine may lead to various adverse reactions, depending on the responsiveness and susceptibility of the vaccinated individual. Cutaneous adverse events are among the most common and can manifest as various local or generalized vaccination react
- 299 Aufrufe
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No abstract supplied.Weiterlesen
- 313 Aufrufe
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No abstract supplied.Weiterlesen
- 92 Aufrufe
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Background and objectives People with skin disease often experience stigmatization in health and body care settings, significantly impacting their quality of life. This parallel-group randomized controlled trial evaluated a face-to-face group seminar aimed at reducing stigma towards people with skin disease among health and body care professionals (HBCPs).Patients and methods Cosmetologists, hairdressers, nurses, and physical therapists were randomized into an intervention (IG; n = 64) or contro
- 53 Aufrufe
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Background and objectives Palmoplantar pustulosis (PPP) is a chronic and refractory inflammatory skin disorder with unclear pathogenesis.Patients and methods Ten PPP patients treated with upadacitinib were monitored to assess efficacy and safety. Immunofluorescence and immunohistochemistry were employed to evaluate Th1, Th2, and Th17 cell expressions, along with their associated cytokines in lesions on palms or soles from 16 PPP patients, 10 chronic eczema (CE) patients, 10 psoriasis vulgaris (P
- 44 Aufrufe
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No abstract supplied.Weiterlesen
- 325 Aufrufe
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Background and objectives Generalized pustular psoriasis (GPP) is a rare, chronic, potentially life-threatening skin disease. We aimed to establish criteria to accurately approximate GPP prevalence in Germany.Methods A retrospective analysis of the WIG2 health claims database (1/1/2016-31/12/2020) was conducted. Patients aged ≥ 12 years continuously enrolled in their statutory health insurance with one inpatient or confirmed outpatient diagnosis code for GPP (International Classification of Dise
- 371 Aufrufe
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No abstract supplied.Weiterlesen
- 99 Aufrufe
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No abstract supplied.Weiterlesen
- 222 Aufrufe
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Background and objectives Knowledge on patient care gaps of prurigo nodularis (PN) is limited. This retrospective chart review (ADVANCE PN) investigated unmet medical needs and gaps in diagnostics, treatment, and management of patients with PN in routine care in Germany.Patients and methods Medical records for adults newly diagnosed with PN between January 2012 and December 2022 from dermatologic clinics and office-based dermatologists were analyzed. Baseline demographics, treatment patterns, di
- 256 Aufrufe
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Generalized pustular psoriasis in a patient with asthma following dupilumab and tezepelumab therapy.
No abstract supplied.Weiterlesen- 279 Aufrufe
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Gluten-related disorders (GRDs) encompass a spectrum of clinical manifestations triggered by gluten ingestion in genetically susceptible individuals. These disorders include celiac disease (CD) and non-celiac gluten sensitivity (NCGS) and present with both intestinal and extraintestinal symptoms, including skin manifestations. Besides the well-known association between CD and dermatitis herpetiformis, considered as the cutaneous manifestation of CD, other dermatoses have been associated to GRDs.
- 231 Aufrufe
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No abstract supplied.Weiterlesen
- 227 Aufrufe
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No abstract supplied.Weiterlesen
- 237 Aufrufe
